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Correspondence: Requests for reprints should be addressed to: Michael X. Repka, M.D., Johns Hopkins University, Wilmer Eye Institute, 600 N. Wolfe St., Wilmer 233, Baltimore, MD 21287-9028; e-mail:mrepka{at}jhmi.edu.
Introduction and Background: The Pediatric Eye Disease Investigator Group is a network of pediatric eye care providers undertaking clinical trials with National Eye Institute support. The network includes university- and community-based providers.
Methods: Randomized and observation studies have involved refining the best amblyopia treatment in children from 3 to less than 18 years of age, observation of the behavior of early-onset esotropia, treatment of primary congenital nasolacrimal duct obstruction, and observation of the stability of strabismic angle in esotropia.
Conclusions: To date 16 studies have been undertaken enrolling 5064 children and teens.
Key words: PEDIG, amblyopia treatment, clinical trials
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